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Sibutramine - Reduce contains Serotonin and Norepinephrin (both substances are very effective, neropinephrin gets into the body of stress and pressure on the fat loss, serotonin and vice versa skľudňuje team is trying to suppress hunger). The drug for obese patients who have a history of cardiovascular disease and are unable to lose weight through diet and exercise. It acts centrally in the brain, where there is a hunger signal. Sibutramine reduces appetite, thus increasing satiety (but not suppress appetite) and increases energy expenditure.